FIBROSIS
ASSAY SERVICES

WHAT IS FIBROSIS?

Thickened, stiff, damaged tissue is the hallmark of fibrosis– a deadly disease that can affect numerous organs and result from a multitude of causes. Currently available treatments are limited, only serving to improve quality of life, so drug-development efforts often target the underlying disease process to identify modulators and inhibitors of the transformation.

In addition to being categorized as a disease in itself, fibrosis is affiliated with other conditions, such as cancer and inflammatory disorders, rendering it a fulcrum point of diverse R&D studies and efforts.

CHALLENGES IN FIBROSIS RESEARCH

The history of failure of anti-fibrotic agents at clinical stages highlights the need for robust, scalable, physiologically relevant assays to maximize the potential of clinical success. Our in vitro assays model various types of fibrosis with cell-culture protocols that minimize basal fibrotic activation to offer quick, reproducible data in a predictable assay window, so you can reduce or avoid the cost- and time-prohibitive barriers inherent to animal models.