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IN VITRO ONCOLOGY & IMMUNO-ONCOLOGY
ASSAY SERVICES

Gain insights into your therapeutic candidates with our in vitro Ready-2-Go assay services, or collaborate with our team to build your customized assay.

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ADVANCING DRUG DEVELOPMENT IN
ONCOLOGY & IMMUNO-ONCOLOGY

Oncology and immuno-oncology (I-O) research has dominated the drug-development field for decades, and the building and understanding of predictive, 2D and 3D human models for assaying novel therapeutics’ impacts continue to evolve. Our assay services use cutting-edge, cell-culture techniques to offer biologically relevant systems, so you can avoid the expense of animal models while expanding assay throughput and shortening the time needed to get actionable data.

READY-2-GO ASSAY SERVICES

Choose from a list of predefined, in vitro assay offerings designed to deliver high-quality data, fast.

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R2G CELL HEALTH

Multiplexed readouts of proliferation, viability, and apoptosis.
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R2G MITOCHONDRIAL HEALTH

Screen for changes in mitochondrial membrane potential.
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R2G LUNG FIBROSIS

Fibrotic induction and inhibition are measured in lung fibroblasts.
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NEW! R2G LIVER FIBROSIS

Fibrotic induction and inhibition are measured in stellate cells.
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NEW! R2G AAV GENE DELIVERY

Assess AAV transduction in various cell types.
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APPLICABLE DISEASES

Preclinical Toxicity Oncology Pulmonary Fibrosis NASH/Liver Cirrhosis Neurodegen.
(AD, PD, MS)		 Psychiatric Disorders Neuro-development
R2G Cell Health ✔ ✔ ✔ ✔
R2G Mitochondrial Health ✔ ✔ ✔ ✔
R2G Lung Fibrosis ✔ ✔
R2G Liver Fibrosis ✔ ✔
R2G AAV Gene Delivery ✔ ✔ ✔ ✔ ✔ ✔
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BUILD YOUR OWN CUSTOM ASSAY

Can't find what you need? Collaborate with our team to design a custom assay suited to your research needs.

  • In vitro models
  • Assay Types
  • Therapeutic Modalities

Examples of in vitro models we use in mono- or multi-cultures:

  • Cell lines (e.g., A549, A-375, HCT116, U-2 OS)
  • Patient-derived xenografts (PDX)
  • PDX-derived cell lines
  • 2D and 3D formats
  • Primary tumor material

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Examples of assays we deliver:

  • Tumor-cell killing
  • Dynamics of 2D vs. 3D responses to therapeutics
  • Immune cell-tumor interaction
  • Influence of tumor microenvironments on therapeutic efficacy and timing 
  • Off-target effects (e.g., cell painting)
  • Cellular uptake or localization of therapeutic agents
  • Subcellular dynamics of proteins, organelles, and trafficking

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Examples of therapeutic modalities we test:

  • Small and large molecules
  • Biologics
  • AAV
  • Lipid nanoparticles (LNP)
  • Lentivirus

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DISCOVER MORE WITH A PARTNER YOU CAN TRUST

"The team at PhenoVista took on a challenging project that required the development and execution of unprecedented, complex assays using healthy and mutant human, iPSC-derived neurons. To get a comprehensive understanding of the system’s biology, PhenoVista can combine several custom palettes for multiplexed imaging, or use their expertise in cell painting to get information through an un-targeted, unbiased approach. They worked with our scientists in a highly collaborative and positive manner and delivered high-quality, useful data that were well interpreted. We would happily work with them again!"

Dr. Julie Selkirk, Associate Director of Biology | Receptos

Summer2022-22

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Let's discuss how we can help with your research.