Skip to content
r2g-liver-fibrosis-banner-v3

READY-2-GO
LIVER FIBROSIS
ASSAY SERVICE

Measure fibrotic induction and inhibition in stellate cells.

 HEPATIC STELLATE CELLS: DRIVERS OF LIVER FIBROSIS

When there is repeated or chronic injury to the liver, the attempts at repair go awry, resulting in fibrosis. Emerging antifibrotic therapies aim to prevent or halt fibrotic induction in hepatic stellate cells (HSCs), the major drivers of this disease.

Our Ready-2-Go Assay Service assesses the effects of your test articles with quantitative, phenotypic readouts to measure fibrotic progression in HSCs.

KEY FEATURES

fibroblasts-icon-v4

Uses human, primary HSCs

fibroblasts-icon-v3

Get readouts that characterize intracellular  and extracellular fibrosis indicators

graph-icon

Only 6-8 weeks from assay to report

well-plates-steps-icon

Option to bundle R2G Services or transition to Custom Services

ASSESS YOUR THERAPEUTICS' EFFECT ON FIBROTIC INDUCTION

HSCs are cultured using a specialized protocol and pre-treated with your test articles. Images are acquired and analyzed at various time points to measure fibrotic induction.

liver-fibrosis-data

AVOID SPECIES DIFFERENCES WITH PRIMARY, HUMAN HSCs

The use of animal models or immortalized cell lines limits clinical translatability. We use primary, human HSCs to circumvent the animals-to-human, translational gap, saving you time and money in your drug-discovery efforts.

translational-gap-v4

 

RELATED READY-2-GO SERVICES

Browse related Ready-2-Go assay offerings. For custom assays, check out our Custom Services.

cell-health-icon

R2G CELL HEALTH

Multiplexed readouts of proliferation, viability, and apoptosis.
Learn more

mitochondrial-health-icon

R2G MITOCHONDRIAL HEALTH

Screen for changes in mitochondrial membrane potential.
Learn more

lung-fibrosis-icon

R2G LUNG FIBROSIS

Fibrotic induction and inhibition are measured in lung fibroblasts.
Learn more

bespoke-services-banner-liver-fibrosis

LEARN MORE ABOUT
CUSTOM ASSAY SERVICES

Can't find what you need? Work with our team to design a custom assay.