We are a leading provider of advanced phenotypic assay services and have built our strong reputation on successfully working with our clients to develop and execute difficult in vitro assays and providing high-quality data to answer complex biological questions. We combine our wide knowledge base with the best-available confocal, fluorescence imaging instrumentation and data-analysis capabilities to solve problems creatively.
Automated microscopy, including the latest confocal systems with integrated image analysis, are the backbone of our services. We use imaging backed up by statistics to give you unparalleled insight into the biological systems you study.
Our imaging platforms include:
- PerkinElmer Operetta CLS High-content Analysis System
- Thermo CellInsight CX7 LED
- Thermo CellInsight CX7 LZR
- Yokogawa CQ1
- GE InCell 6500HS
- Thermo Cellomics ArrayScan VTI
- ECHO Revolve Fluorescence Microscope
- Sartorius Incucyte
- Araceli Endeavor
Additional assay resources and equipment include:
- Partner and preferred-provider access to FUJIFILM Cellular Dynamics, Inc. products
- Yamaha Motors Cell Handler for spheroid and organoid handling
- Microfluidic and Organ-chip Systems
- Rastrum 3D Bioprinter
We use the following state-of-the-art, liquid-handling automation platforms:
- Apricot 384-tip liquid-handling robots
- I.DOT 384- or 1536-tip liquid handler
- Tecan D300 digital dispenser
- Opentrons OT-2 liquid handler
ANALYSIS & COMPUTATION
Phenotypic screening can generate large and complex datasets rife with image-analysis jargon. We handle that for you. As biologists with industry experience, we know what is relevant and what is not. We’ll make the data palatable to the audience who whom you are presenting, whether it be colleagues, members of another scientific field, or executive management.
- Dedicated multi-GB network and multi-TB cloud-based computing
- Machine-learning and image deconvolution
- Professionally managed IT environment with data backup and disaster recovery
High-content imaging is a flexible and powerful multi-layered strategy for generating comprehensive data prior to the late pre-clinical to clinical phases of drug development. Our team at PhenoVista specializes in in vitro assay development using cutting-edge imaging techniques, equipment, and data analysis techniques to support your research.
ASSAY SERVICE OFFERINGS
Our expertise relies on the use of physiologically relevant cell models and high-content imaging to get you actionable insights into the effects of your therapeutic agents in various areas of disease research.
IMAGING & ANALYSIS
You send us plates with cells that have been fixed & stained, we'll send you data.
Defined, fixed offerings across a range of disease and therapeutic areas.
Handle a large number of compounds and compare against known drugs.
Custom assays to answer more specific, complex biological questions.
OUR PEOPLE SET US APART
Our team of predominantly PhD-level scientists has diverse expertise ranging from biomedical engineering to neurobiology. We work with clients in a collaborative, adaptable manner to design and implement physiologically meaningful assays to help answer their biological questions. Our team’s repertoire includes working with primary cells, iPSC-derived neurons and glia, and client-engineered lines in a variety of formats such as 2D, 3D, co-culture, and microfluidic systems. Our team delivers unique and cutting-edge functional, structural, and pre-clinical, mechanistic data to clients globally.
Let's discuss how we can help with your research.