UNDERSTAND
COMPLEX BIOLOGY,
FASTER
We develop and execute difficult in vitro assays with precision and speed. Our best-in-class team works with leading biotech and pharmaceutical companies around the world to answer their complex biological questions.
UNDERSTAND COMPLEX BIOLOGY, FASTER
We develop and execute difficult in vitro assays with precision and speed. Our best-in-class team works with leading biotech and pharmaceutical companies around the world to answer their complex biological questions.
IN VITRO ASSAYS PLAY A KEY ROLE IN DRUG DISCOVERY
In vitro assays offer a cost-effective, efficient, and highly reliable way to screen candidate compounds in the early stages of drug development. Whether identifying promising, novel agents or aiming to enhance existing treatments, in vitro assays can be applied to a wide range of systems, from simple mono-cultures of immortalized cell lines to complex cultures of patient-derived tissue samples or iPSC-derived cells.
Benefits include:
- Scalable to high-throughput formats
- Ability to isolate, control, and study specific pathways or systems of interest
- Fast turnaround time compared to in vivo assays
PHENOTYPIC STUDIES PLAY A KEY ROLE IN DRUG DISCOVERY
High-stakes decision making is at the heart of drug discovery and development. Uncertainty about targets, mechanisms of action, and whether to advance or abandon candidate compounds is the norm.
Because they provide only limited data, conventional low-plex in vitro assays don’t bring enough clarity to these complex questions.
With our expertise in the development and use of high-content imaging-based phenotypic assays, we deliver the biological insights and high-quality data you need to inform and de-risk R&D decisions.
PHENOTYPIC STUDIES PLAY A KEY ROLE IN DRUG DISCOVERY
High-stakes decision making is at the heart of drug discovery and development. Uncertainty about targets, mechanisms of action, and whether to advance or abandon candidate compounds is the norm.
Because they provide only limited data, conventional low-plex in vitro assays don’t bring enough clarity to these complex questions.
With our expertise in the development and use of high-content imaging-based phenotypic assays, we deliver the biological insights and high-quality data you need to inform and de-risk R&D decisions.
THE DRUG DEVELOPMENT PIPELINE
EMPOWERING MORE EFFECTIVE R&D
WITH HIGH-QUALITY DATA
Mechanism of Action
Target Dynamics
Therapeutic Efficacy
Therapeutic Uptake
AAV Dynamics
Subcellular Behavior
RESOURCES
CLOSING THE TRANSLATIONAL GAP WITH RELEVANT CELL MODELS
Animal models do not mirror human biology. At PhenoVista, we can work with human cell models to ensure repeatable, reliable, and clinically translatable data.
OUR APPROACH
One assay does not fit all. We leverage the strengths and benefits of a variety of instruments, rather than manipulate assays and conditions to fit a specific piece of equipment. This empowers us to tackle problems from multiple perspectives.
- Thermo CellInsight CX7 LED
- Thermo CellInsight CX7 LZR
- Yokogawa CQ1
- GE InCell 6500HS
- Thermo Cellomics ArrayScan VTI
- ECHO Revolve Fluorescence Microscope
- Sartorius Incucyte
- Araceli Endeavor
Automation - Apricot 384-tip liquid-handling robots
- I.DOT 384- or 1536-tip liquid handler
- Tecan D300 digital dispenser
- Opentrons OT-2 liquid handler
Analysis & Computation - Dedicated multi-GB network and multi-TB cloud-based computing
- Machine-learning and image deconvolution
- Professionally managed IT environment with data backup and disaster recovery
EXPLORE OUR SERVICE OFFERINGS
Our expertise relies on the use of physiologically relevant cell models and high-content imaging to get you actionable insights into the effects of your therapeutic agents in various areas of disease research.
CUSTOM ASSAYS
Custom assays to answer your specific, complex biological questions.
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READY-2-GO
Defined assay offerings across a range of disease and therapeutic areas.
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CELL PAINTING
Compare your compounds' effects against those of reference compounds.
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IMAGING & ANALYSIS
You send us plates with cells that have been fixed & stained, and we'll send you data.
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CONTACT US
Let's discuss how we can help with your research.