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READY-2-GO
LUNG FIBROSIS
ASSAY SERVICE

Measure fibrotic induction and inhibition in human, primary lung fibroblasts.

 IDENTIFY FIBROTIC MODULATORS AND INHIBITORS

Thickened, stiff, damaged lung tissue is the hallmark of lung fibrosis – a deadly disease that can result from a multitude of causes, including environmental insults, chronic infection, or genetic factors. Progression of fibrosis manifests through the biosynthesis of extracellular matrix proteins and intracellular stress fibers.

Our Ready-2-Go assay service assesses the effects of your test articles on fibrotic induction using primary, human lung fibroblasts.

KEY FEATURES

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Uses human, primary cells in an in vitro model of lung fibrosis

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Readouts that characterize intracellular and extracellular fibrosis indicators

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Only 6-8 weeks from assay to report

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Option to bundle R2G Services or transition to Custom Services

ASSESS YOUR THERAPEUTICS' EFFECT ON FIBROTIC INDUCTION

Primary, human, normal lung fibroblasts are treated with your test articles prior to fibrotic induction, and images are acquired and analyzed at various time points.

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AVOID SPECIES DIFFERENCES WITH PRIMARY, HUMAN, LUNG FIBROBLASTS

The use of animal models or immortalized cell lines limits clinical translatability. We use primary, human, lung fibroblasts to help bridge the gap between the bench and clinic.

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RELATED READY-2-GO SERVICES

Browse related Ready-2-Go assay offerings. For custom assays, check out our Custom Services.

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Multiplexed readouts of proliferation, viability, and apoptosis.
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Screen for changes in mitochondrial membrane potential.
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Fibrotic induction and inhibition are measured in stellate cells.
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LEARN MORE ABOUT
CUSTOM ASSAY SERVICES

Can't find what you need? Work with our team to design a custom assay.