OVERVIEW
Cell painting is a scalable, fluorescence imaging-based method that provides detailed, unbiased, comprehensive information about therapeutic candidates without a priori knowledge of their impact on cells. Cell painting is used in many drug-development campaigns and can drive forward your research through various applications, including mechanism of action (MOA) determination, toxicity profiling, and target identification.
To aid in our clients’ R&D programs, we specialize in developing in vitro, phenotypic screening assays that range from simple, monocultures to complex, multi-cell type models. We collaborate with our clients to design custom assays that will answer their most pressing questions.
HIGHLIGHTS
We outline a cell-painting study that used human, iPSC-derived hepatocytes, including
- An overview of cell painting and its uses in drug discovery
- Representative images
- Uniform Manifold Approximation and Projection (UMAP)
- Dendrogram and heat map
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Overview
Learn more about how cell painting is used in drug-discovery applications and review an example using human, iPSC-derived hepatocytes.
Highlights
- Overview of cell painting and its uses in drug discovery
- Representative images
- Uniform Manifold Approximation and Projection (UMAP)
- Dendrogram and heat map