CASE STUDY

Evaluating Candidate AAV Therapies' Transduction Efficiencies in a Model of Parkinson's Disease

Review an example of a study designed to measure transduction efficiencies of AAV gene-therapy candidates in a model of Parkinson's disease.

OVERVIEW

A client requested a custom project to evaluate transduction efficiencies of AAV gene-therapy candidates in a model of Parkinson's disease.

Representative images showing uptake and transduction of AAV in WT and KO (-/-) dopaminergic neurons.

Browse representative images and data evaluating AAV uptake and transduction in human, iPSC-derived WT and KO dopaminergic neurons.

APP NOTE

Learn about Parkinson's disease (PD) and review examples of phenotypic studies designed to measure aspects of PD-relevant biology.

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Review an example study evaluating the protective efficacy of a therapeutic candidate in ALS-relevant co-cultures of motor neurons and astrocytes.

CASE STUDY

Review an example study using a custom, neuronal tri-culture model to evaluate a therapeutic agent's effects on various health metrics.

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Overview

Review an example of a study designed to measure fibrosis induction and inhibition in hepatic stellate cells (HSCs).

Highlights