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READY-2-GO
NEURITE OUTGROWTH
ASSAY SERVICE

Assess the effects of your compound on neuronal development in human, iPSC-derived neurons.

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 NEURITE OUTGROWTH: A KEY ASPECT OF NEURONAL DEVELOPMENT

Neurites, comprised of axons and dendrites, form the functional network by which neurons connect to enable signal transduction and proper development and differentiation. The ability of neurons to grow these networks determines their overall effectiveness at carrying out their functions. 

Our Ready-2-Go Assay Service assesses your test articles’ effects on neuronal development in new or developing human, iPSC-derived glutamatergic neurons to provide actionable insights into the safety and toxicity of your therapeutic candidate.

KEY FEATURES

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Uses human, iPSC-derived neurons

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Quantitative, morphological measurements of neurites and soma

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Only 4-6 weeks from assay to report

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Option to bundle R2G Services or transition to Custom Services

ASSESS YOUR THERAPEUTICS' EFFECT ON NEURITE OUTGROWTH

Human, iPSC-derived, glutamatergic neurons are treated with reference compounds and your test articles shortly after seeding. Images are then acquired and analyzed at various time points for various neurite-outgrowth metrics.

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AVOID SPECIES DIFFERENCES WITH HUMAN, iPSC-DERIVED NEURONS

The use of animal models or immortalized cell lines limits clinical translatability. We use human, iPSC-glutamatergic neurons to help bridge the gap between the bench and clinic.

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RELATED READY-2-GO SERVICES

Browse related Ready-2-Go assay offerings. For custom assays, check out our Custom Services.

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Multiplexed readouts of viability and apoptosis.
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Multiplexed readouts of mitochondrial health.
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R2G MICROGLIA PHAGOCYTOSIS

Measure uptake of a fluorescent bacterial bioparticle by human, iPSC-derived human microglia.
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R2G NEURITE NETWORK DYNAMICS

Quantification of changes in established neurite networks using human, iPSC-derived neurons.
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LEARN MORE ABOUT
CUSTOM ASSAY SERVICES

Can't find what you need? Work with our team to design a custom assay.
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