READY-2-GO
NEURITE NETWORK DYNAMICS
ASSAY SERVICE
Assess the effects of your compound on established neurite networks using human, iPSC-derived neurons.
KEY FEATURES
Uses human, iPSC-derived neurons
Quantitative, morphological measurements of neurites and soma
Only 6-8 weeks from assay to report
Option to bundle R2G Services or transition to Custom Services
ASSESS YOUR THERAPEUTICS' EFFECT ON NEURITE NETWORKS
Human, iPSC-derived, glutamatergic neurons are cultured for a week before treatment with reference compounds and your test articles. Images are then acquired and analyzed at various time points to assess changes in neurite-network metrics.
AVOID SPECIES DIFFERENCES WITH HUMAN, iPSC-DERIVED NEURONS
The use of animal models or immortalized cell lines limits clinical translatability. We use human, iPSC-derived glutamatergic neurons to help bridge the gap between the bench and clinic.
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