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CASE STUDY

Lipid-droplet Formation in Human, iPSC-derived Hepatocytes

Review a study that evaluates a therapeutic candidate's ability to inhibit lipid-droplet formation in human, iPSC-derived hepatocytes.

OVERVIEW

A client requested a custom project assessing whether their therapeutic candidate can inhibit lipid-droplet formation in human, iPSC-derived hepatocytes.

HIGHLIGHTS

  • Overview of study objective and goals
  • Experimental design, including timelines and deliverables
  • Representative images and graphs
  • Study results

REPRESENTATIVE IMAGES

Representative images of human, iPSC-derived hepatocytes treated with palmitic acid (PA) and oleic acid (OA).

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DOWNLOAD THE COMPLETE CASE STUDY

Browse representative images and data evaluating a therapeutic agent's ability to inhibit lipid-droplet formation in hepatocytes. 

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RELATED RESOURCES

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APP NOTE

Cell Painting App Note

Learn more about how cell painting is used in drug-discovery applications and review an example using human, iPSC-derived hepatocytes.

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BLOG POST

Addressing Lipotoxicity in Fibrosis: Pharmaceutical Approaches and Implications

Lipotoxicity is a driver of fibrosis, and new drug-development strategies are targeting this phenomenon as a potential avenue for treatment.

Adipocytes stained with Hoechst, BODIPY, and MitoTracker Deep Red FM.

BLOG POST

Understanding Fat Metabolism: White Fat vs Brown Fat and Bear Hibernation

Learn about species differences between humans and bears in regards to white and brown adipose tissue and their role in maintaining metabolic health.

CONTACT US

Let's discuss how we can help with your next study.

DOWNLOAD THE CASE STUDY

Evaluating a Therapeutic Candidate's Protective Efficacy in ALS-relevant, Motor-neuron Co-culture Models

Overview

Review an example of a study evaluating the protective efficacy of a therapeutic candidate in ALS-relevant co-cultures of motor neurons and astrocytes.

Highlights

  • Overview of study objective and goals
  • Experimental design, including timelines and deliverables
  • Representative images and graphs
  • Study results

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