Skip to content
Close
SEARCH
Store
Contact Us
Store
Contact Us
SERVICE OFFERINGS
RESEARCH AREAS
COMPANY OVERVIEW
LEARNING LIBRARY
r2g-neuronal-mitohealth-banner-v3

READY-2-GO
NEURONAL MITOCHONDRIAL HEALTH
ASSAY SERVICE

Measure mitochondrial location and function in human, iPSC-derived, glutamatergic neurons.

DOWNLOAD BROCHURE

 MITOCHONDRIAL DYSFUNCTION: A HALLMARK OF MANY NEURODEGENERATIVE DISEASES

Assessing mitochondrial health in early-stage drug development is proving crucial in understanding drug candidates' impact on the broader, cell-health continuum. As mitochondrial malfunction is increasingly implicated in the onset of neuronal dysfunction/death in diseases such as Alzheimer’s, Parkinson’s, and dementia, efforts in developing drugs that mitigate these effects are expanding. 

Our Ready-2-Go Assay Service provides multiplexed measurements of mitochondrial quantity, location, and functionality using human, iPSC-derived, glutamatergic neurons.

KEY FEATURES

neuron-icon-v3

Uses human, iPSC-derived neurons

neuronal-mitochondrial-health-icon

Multiplexed measurements of mitochondrial location and function

graph-icon

Only 6-8 weeks from assay to report

well-plates-steps-icon

Option to bundle R2G Services or transition to Custom Services

ASSESS YOUR THERAPEUTICS' EFFECT ON MITOCHONDRIAL HEALTH

Human, iPSC-derived, glutamatergic neurons are treated with reference compounds alongside your test articles. Images are then acquired and analyzed at various time points to assess changes in mitochondrial location and membrane potential.

Get More Information
neuronal-mitohealth-data

AVOID SPECIES DIFFERENCES WITH HUMAN, iPSC-DERIVED NEURONS

The use of animal models or immortalized cell lines limits clinical translatability. We use human, iPSC-glutamatergic neurons to help bridge the gap between the bench and clinic.

translational-gap-v5

 

RELATED READY-2-GO SERVICES

Browse related Ready-2-Go assay offerings. For custom assays, check out our Custom Services.

neurotoxicity-icon

R2G NEUROTOXICITY

Multiplexed readouts of viability and apoptosis.
Learn more

neuronal-outgrowth-network-icon

R2G NEURITE OUTGROWTH & NEURITE NETWORK DYNAMICS

Quantification of neurite outgrowth and changes in established neurite networks using human, iPSC-derived neurons.
Learn more

microglia-phagocytosis-icon

R2G MICROGLIA PHAGOCYTOSIS

Measure uptake of a fluorescent bacterial bioparticle by human, iPSC-derived microglia.
Learn more
bespoke-services-banner-neuro-mitohealth

LEARN MORE ABOUT
CUSTOM ASSAY SERVICES

Can't find what you need? Work with our team to design a custom assay.
EXPLORE CUSTOM OPTIONS