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READY-2-GO
NEURONAL MITOCHONDRIAL HEALTH
ASSAY SERVICE

Measure mitochondrial location and function in human, iPSC-derived, glutamatergic neurons.

 MITOCHONDRIAL DYSFUNCTION: A HALLMARK OF MANY NEURODEGENERATIVE DISEASES

Assessing mitochondrial health in early-stage drug development is proving crucial in understanding drug candidates' impact on the broader, cell-health continuum. As mitochondrial malfunction is increasingly implicated in the onset of neuronal dysfunction/death in diseases such as Alzheimer’s, Parkinson’s, and dementia, efforts in developing drugs that mitigate these effects are expanding. 

Our Ready-2-Go Assay Service provides multiplexed measurements of mitochondrial quantity, location, and functionality using human, iPSC-derived, glutamatergic neurons.

KEY FEATURES

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Uses human, iPSC-derived neurons

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Multiplexed measurements of mitochondrial location and function

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Only 6-8 weeks from assay to report

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Option to bundle R2G Services or transition to Custom Services

ASSESS YOUR THERAPEUTICS' EFFECT ON MITOCHONDRIAL HEALTH

Human, iPSC-derived, glutamatergic neurons are treated with reference compounds alongside your test articles. Images are then acquired and analyzed at various time points to assess changes in mitochondrial location and membrane potential.

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AVOID SPECIES DIFFERENCES WITH HUMAN, iPSC-DERIVED NEURONS

The use of animal models or immortalized cell lines limits clinical translatability. We use human, iPSC-glutamatergic neurons to help bridge the gap between the bench and clinic.

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LEARN MORE ABOUT
CUSTOM ASSAY SERVICES

Can't find what you need? Work with our team to design a custom assay.
EXPLORE CUSTOM OPTIONS