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READY-2-GO
NEUROTOXICITY
ASSAY SERVICE

Measure apoptosis and cell viability using human, iPSC-derived neurons.

 NEURONAL VIABILITY: AN INDISPENSABLE INDICATOR OF DRUG SAFETY & TOXICITY

Evaluating the impacts of drug candidates on cell viability are required for moving therapeutic candidates into the clinic, but distinguishing between mechanisms of death can prove challenging. It is crucial that CNS-targeting drugs do not compromise cell health and that drugs that do not target the CNS do not have off-target effects.

Our Ready-2-Go Assay Service uses multiplexed dyes to simultaneously measure apoptosis and viability in human, iPSC-derived glutamatergic neurons.

KEY FEATURES

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Uses human, iPSC-derived neurons

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Multiplexed measurements of apoptosis and cell viability

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Only 6-8 weeks from assay to report

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Option to bundle R2G Services or transition to Custom Services

ASSESS YOUR THERAPEUTICS' EFFECT ON NEURONAL VIABILITY

Human, iPSC-derived neurons are treated with reference compounds alongside your test articles. Images are then acquired and analyzed at various time points to assess changes in cell viability.

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AVOID SPECIES DIFFERENCES WITH HUMAN, iPSC-DERIVED NEURONS

The use of animal models or immortalized cell lines limits clinical translatability. We use human, iPSC-derived neurons to help bridge the gap between the bench and clinic.

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Browse related Ready-2-Go assay offerings. For custom assays, check out our Custom Services.

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Quantification of neurite outgrowth and changes in established neurite networks using human, iPSC-derived neurons.
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R2G MICROGLIA PHAGOCYTOSIS

Measure uptake of a fluorescent bacterial bioparticle by human, iPSC-derived microglia.
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LEARN MORE ABOUT
CUSTOM ASSAY SERVICES

Can't find what you need? Work with our team to design a custom assay.
EXPLORE CUSTOM OPTIONS