We Continue To Support Your Research
At PhenoVista we strive to enable medical researchers to profoundly impact both individual patients and the healthcare system through our high content imaging services. During this difficult time we are practicing social distancing to reduce the risk of spreading the novel coronavirus in our communities while continuing to support our research partners.
Our sincere thanks and gratitude goes out to all the medical professionals, healthcare workers, fellow researchers, policy makers, and first responders who are working to help those affected by this pandemic.
ASSAYS FOR COVID-19 RESEARCH
SOME OF OUR ASSAYS RELATED TO COVID-19 RESEARCH:
- VIRAL ENTRY
- MECHANISM OF ACTION AND REPURPOSING STUDIES
Viral Entry in Primary Human Endothelial Cells
Assay measures SARS-COV2 spike protein / ACE2 receptor dependent entry into endothelial cells using reagents developed by Montana Molecular. HUVECs were transduced with ACE2 receptor, then infected with baculovirus pseudotyped with SARS-COV2 spike protein. Pretreatment with the known entry inhibitor lactoferrin (Mirabelli et al., 2020) showed dose-dependent inhibition. (*) = SSMD <-2.0.